规格: | 98% |
分子量: | 0 |
包装 | 价格(元) |
10mg | 电议 |
50mg | 电议 |
Background:
Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through thede novosynthesis pathway, which requires the coordinated action of serine palmitoyl transferase and ceramide synthase. They have been shown to mediate antiproliferative responses such as apoptosis, growth arrest, differentiation, and senescence.1This product contains a mixture of hydroxy fatty acid-containing ceramides. [Matreya, LLC. Catalog No. 1323]
1.Ogretmen, B., Pettus, B.J., Rossi, M.J., et al.Biochemical mechanisms of the generation of endogenous long chain ceramide in response to exogenous short chain ceramide in the A547 human lung adenocarcinoma cell lineJ. Biol. Chem.277(15)12960-12969(2002)