A fungal metabolite
货号:ajcx21774
CAS:149466-04-6
分子式:C27H24O7
分子量：460.5
溶解度:Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

BE-24566B is a polyketide fungal metabolite originally isolated fromS. violaceusniger.¹It is active againstB. subtilis,B. cereus,S. aureus,M. luteus,E. faecalis, andS. thermophilus(MICs = 1.56, 1.56, 1.56, 1.56, 3.13, and 3.13 µg/ml, respectively). BE-24566B is an endothelin (ET) receptor antagonist (IC₅₀s = 11 and 3.9 µM for ET_Aand ET_Breceptors, respectively).²

1.Kojiri, K., Nakajima, S., Fuse, A., et al.BE-24566B, a new antibiotic produced by Streptomyces violaceusnigerJ. Antibiot. (Tokyo)48(12)1506-1508(1995) 2.Lam, Y.K.T., Hensens, O., Helms, G., et al.L-755,805, a new polyketide endothelin binding inhibitor from an actinomyceteTetrahedron Lett.36(12)2013-2016(1995)