C19H14FN5O
货号:ajcx19676
CAS:2131223-69-1
分子式:C19H14FN5O
分子量：347.3
溶解度:Chloroform: 30 mg/ml,DMF: 5 mg/ml,DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

YW1159 is an inhibitor of Wnt signaling with an IC50 value of 1.2 nM in a reporter assay.1,2 It is not cytotoxic to HEK293 cells following incubations of up to 24 hours but cell viability is decreased in a concentration-dependent manner after 72 hours.2

参考文献
2. Obianom, O.N., Ai, Y., Li, Y., et al. Triazole-based inhibitors of the Wnt/β-catenin signaling pathway improve glucose and lipid metabolism in diet-induced obese mice. J. Med. Chem. 62(2), 727-741 (2019).