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YW1159
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
YW1159图片
规格:98%
分子量:347.3
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
C19H14FN5O
货号:ajcx19676
CAS:2131223-69-1
分子式:C19H14FN5O
分子量:347.3
溶解度:Chloroform: 30 mg/ml,DMF: 5 mg/ml,DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

YW1159 is an inhibitor of Wnt signaling with an IC50 value of 1.2 nM in a reporter assay.1,2 It is not cytotoxic to HEK293 cells following incubations of up to 24 hours but cell viability is decreased in a concentration-dependent manner after 72 hours.2

参考文献
2. Obianom, O.N., Ai, Y., Li, Y., et al. Triazole-based inhibitors of the Wnt/β-catenin signaling pathway improve glucose and lipid metabolism in diet-induced obese mice. J. Med. Chem. 62(2), 727-741 (2019).