FAK inhibitor 2 是一种有效的粘着斑激酶 (FAK) 抑制剂,IC50 值为 0.07?nM,有抗肿瘤和抗血管生成活性。
货号:ajcx13894
CAS:2354405-14-2
分子式:C29H33F3N8O2S2
分子量:646.75
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
FAK inhibitor 2 is a potent focal adhesion kinase (FAK) inhibitor with an IC50 ?of 0.07?nM, with antitumor and anti-angiogenesis activities[1].
IC50: 0.07?nM (FAK)[1]
[1]. Su Y, et al. Discovery of 2,4-diarylaminopyrimidine derivatives bearing dithiocarbamate moiety as novel FAK inhibitors with antitumor and anti-angiogenesis activities. Eur J Med Chem. 2019 May 18;177:32-46.