SGC3027 是一种组蛋白甲基转移酶抑制剂。SGC3027 是第一个有效,选择性,具有细胞活性的?PRMT7?化学探针。
货号:ajcx12142
CAS:2624313-13-7
分子式:C??H??ClN?O?S
分子量:787.37
溶解度:DMSO : 250 mg/mL
纯度:98%
存储:Store at -20°C
库存:
现货Background:
SGC3027 is a?histone methyltransferase?inhibitor[1]. SGC3027 is the first potent, selective and cell active chemical probe for?PRMT7[2]
SGC3027 is a pro-drug of SGC8158 which releases the active component upon reduction in the cell by reductases. In cellular assays using C2C12 cells, SGC3027 inhibits the methylation of HSP70 with IC50=1.3 μM[2].