Secaubryenol 是一类从 Coussarea macrophylla 中分离的 3,4-七环烷三萜。Secaubryenol 在 10 µg/mL 的剂量下不显示任何细胞毒性。
货号:ajcx35180
CAS:925932-08-7
分子式:C30H48O3
分子量：456.7
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Secaubryenol is a class of 3,4-secocycloartane triterpenes isolated from Coussarea macrophylla. Secaubryenol does not display any cytotoxic effect at a dose of 10 µg/mL[1][2][3].

Secaubryenol exhibits IC50 value over 100 µM against tumor cell lines (MCF-7 (breast cancer cells, ER (estrogen receptor) positive), MDA (breast cancer cells, ER negative), PC-3 (prostate cancer cells), and HeLa (cervical cancer cells))[1].

[1]. Grougnet R, et al. Cytotoxic 3,4-seco-cycloartane triterpenes from the exudate of Gardenia tubifera. J Nat Prod. 2006 Dec;69(12):1711-4.
[2]. Gilardoni G, et al. New 3,4-Secocycloartane and 3,4-Secodammarane Triterpenes from the Ecuadorian Plant Coussarea macrophylla. Chem Biodivers. 2015 Jun;12(6):946-54.
[3]. ThanesuanNuanyai, et al. Cycloartane triterpenes from the exudate of Gardenia thailandica. Phytochemistry Letters. Volume 4, Issue 1, 15 March 2011, Pages 26-29.