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Azido-PEG8-Boc
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Azido-PEG8-Boc图片
规格:98%
分子量:523.62
包装与价格:
包装价格(元)
100mg电议
500mg电议

产品介绍
Azido-PEG8-Boc是一种PROTAClinker,属于PEG和Alkyl/ether类,可用于合成PROTAC。
货号:ajcx31972
CAS:1623791-99-0
分子式:C23H45N3O10
分子量:523.62
溶解度:DMSO: 200 mg/mL (381.96 mM)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Azido-PEG8-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].


[1]. Garofalo, Antonio, et al. Efficient synthesis of small-sized phosphonated dendrons: potential organic coatings of iron oxide nanoparticles. New Journal of Chemistry (2014), 38(11), 5226-5239.