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GIP(1-30)amide,Human acetate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GIP(1-30)amide,Human acetate图片
规格:98%
分子量:3591.99
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
GIP (1-30) amide,Human acetate 是葡萄糖依赖性促胰岛素多肽 (GIP) 片段。葡萄糖依赖性促胰岛素多肽是一种肠降血糖素激素,可刺激胰岛素分泌并减少餐后血糖波动。GIP (1-30) amide (Human) 在 10-9-10-6 M 范围内剂量依赖性地促进胰岛素分泌。
货号:ajcx29362
CAS:N/A
分子式:C164H244N40O49S
分子量:3591.99
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

GIP (1-30) amide,Human acetate is a glucose-dependent insulinotropic polypeptide (GIP) fragment. GIP is an incretin hormone that stimulates insulin secretion and reduces postprandial glycaemic excursions. GIP (1-30) amide (Human) dose-dependently promotes insulin secretion over the range 10-9-10-6 M[1].

The glucose-dependent action of Glucose-dependent insulinotropic polypeptide (GIP) on pancreatic β-cells has attracted attention towards its exploitation as a potential drug for type 2 diabetes. In a 50% aqueous trifluoroethanol solvent, GIP(1-30) amide has an α-helical structural region from F6 to A28. The structures calculated for GIP(1-30) amide remain within one family of conformations and the level of agreement between the structures demonstrated the ordered arrangement[1].


[1]. AlaÑa I, et al. NMR structure of the glucose-dependent insulinotropic polypeptide fragment, GIP(1-30)amide. Biochem Biophys Res Commun. 2004 Dec 3;325(1):281-6.