| 包装: | 50mg |
| 规格: | 98% |
| 市场价: | 5733元 |
| 分子量: | 488.6 |
Background:
Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand with terminal hydroxyl ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Maniaci et al (2017) Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat.Comm. 8 830 PMID:29018234
m.cnreagent.com