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α-Muricholic Acid-d4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
α-Muricholic Acid-d4图片
包装:1mg
规格:98%
市场价:2963元
分子量:412.6

产品介绍
An internal standard for the quantification of α-muricholic acid
货号:ajcx24998
CAS:N/A
分子式:C24H36D4O5
分子量:412.6
溶解度:DMF: 30 mg/ml,DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

α-Muricholic acid-d4is intended for use as an internal standard for the quantification of α-muricholic acid by GC- or LC-MS. α-Muricholic acid is a murine-specific primary bile acid.1,2Dietary administration of soybean protein decreases fecal levels of α-muricholic acid in mice with high-fat diet-induced obesity, which correlates with increases in fecalClostridiumcluster XIVa, a major producer of secondary bile acids.3Plasma, liver, and muscle levels of α-muricholic acid are increased in mice switched from a high-fat to low-fat diet.4


1.Eyssen, H.J., Parmentier, G.G., and Mertens, J.A.Sulfate bile acids in germ-free and conventional miceEur. J. Biochem.66(3)507-514(1976) 2.Uehara, T., Xi Peng, X., Bennett, B., et al.c-Jun N-terminal kinase mediates hepatic injury after rat liver transplantationTransplantation78(3)324-332(2004) 3.Watanabe, K., Igarashi, M., Li, X., et al.Dietary soybean protein ameliorates high-fat diet-induced obesity by modifying the gut microbiota-dependent biotransformation of bile acidsPLoS One13(8)e0202083(2018) 4.La Frano, M.R., Hernandez-Carretero, A., Weber, N., et al.Diet-induced obesity and weight loss alter bile acid concentrations and bile acid-sensitive gene expression in insulin target tissues of C57BL/6J miceNutr. Res.4611-21(2017)