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MitoB-d15
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
MitoB-d15图片
规格:98%
分子量:492.2
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
A neuropeptide with diverse biological activities
货号:ajcx22964
CAS:N/A
分子式:C25H8D15BO2P.Br
分子量:492.2
溶解度:DMF: 5 mg/ml,DMSO: 10 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml,Ethanol: 0.5 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

MitoB-d15is intended for use as an internal standard for the quantification of MitoB by GC- or LC-MS. MitoB is a ratiometric mass spectrometry probe that can be used for assessing changes in H2O2within mitochondriain vivo. MitoB contains a triphenylphosphonium cation component that drives its accumulation in mitochondria where its arylboronic moiety selectively reacts with H2O2to produce a phenol product, MitoP .1,2Quantifying the MitoP/MitoB ratio by LC-MS/MS reflects the mitochondrial matrix H2O2concentration.


1.CochemÉ, H.M., Logan, A., Prime, T.A., et al.Using the mitochondria-targeted ratiometric mass spectrometry probe MitoB to measure H2O2 in living DrosophilaNature Protocols7(5)946-958(2012) 2.CochemÉ, H.M., Quin, C., McQuaker, S.J., et al.Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrixCell Metabolism13(3)340-350(2011)