HPK1-IN-8 是一种变构、非活性构象选择性全长 HPK1 抑制剂。
货号:ajcx35444
CAS:1214561-09-7
分子式:C19H17FN6O2S
分子量:412.44
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
HPK1-IN-8 is an allosteric, inactive conformation-selective inhibitor of full-length HPK1.
[1]. Wang W, et al. Discovery of an Allosteric, Inactive Conformation-Selective Inhibitor of Full-Length HPK1 Utilizing a Kinase Cascade Assay. Biochemistry. 2021 Oct 19;60(41):3114-3124.