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Strictosidinic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Strictosidinic acid图片
包装:1mg
规格:98%
市场价:4410元
分子量:516.54

产品介绍
Strictosidinicacid是一种具有口服活性的,从Psychotriamyriantha叶中分离的糖苷吲哚单萜生物碱,抑制5-HT生物合成的前体酶并降低5-HT含量。Strictosidinicacid在小鼠中具有外周镇痛和解热活性。
货号:ajcx32366
CAS:150148-81-5
分子式:C26H32N2O9
分子量:516.54
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Strictosidinic acid, an orally active glycoside indole monoterpene alkaloid isolated from Psychotria myriantha leaves, inhibits precursor enzymes of 5-HT biosynthesis and reduces the 5-HT levels. Strictosidinic acid has peripheral analgesic and antipyretic activities in mice[1][2].


Strictosidinic acid (20 μg/μl; intra-hippocampal injection) causes a significance of 83.5% reduction in 5-HT levels. Strictosidinic acid (10 mg/kg; i.p.) causes a 63.4% reduction in 5-HT levels and a 67.4% reduction in DOPAC values in male Wistar rats, weighing 200-250 g[1].

[1]. F M Farias, et al. Strictosidinic Acid, Isolated From Psychotria Myriantha Mull. Arg. (Rubiaceae), Decreases Serotonin Levels in Rat Hippocampus. Fitoterapia. 2012 Sep;83(6):1138-43. [2]. F M Farias, et al. Monoamine Levels in Rat Striatum After Acute Intraperitoneal Injection of Strictosidinic Acid Isolated From Psychotria Myriantha Mull. Arg. (Rubiaceae). Phytomedicine. 2010 Mar;17(3-4):289-91.