您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Calmodulin-Dependent Protein Kinase II(290-309)acetate
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Calmodulin-Dependent Protein Kinase II(290-309)acetate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
规格:98%
分子量:2333.88
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Calmodulin-DependentProteinKinaseII(290-309)acetate是有效的CaMK拮抗剂,抑制抑制Ca2+/钙调蛋白依赖性蛋白激酶II的IC50值为52nM。
货号:ajcx31932
CAS:N/A
分子式:C105H189N31O26S
分子量:2333.88
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Calmodulin-Dependent Protein Kinase II (290-309) acetate is a potent CaMK antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase II[1].

Peptide 290 to 309 is found to be a potent calmodulin antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase. Neither truncation from the amino terminus (peptide 296-309) nor extension in the carboxyl-terminal direction (peptide 294-319) markedly affects calmodulin binding, whereas shortening the peptide from the carboxyl terminus (peptide 290-302) or from both ends (peptide 295-304) results in the elimination of this activity[1].


[1]. Payne ME, et al. Calcium/calmodulin-dependent protein kinase II. Characterization of distinct calmodulin binding and inhibitory domains. J Biol Chem. 1988 May 25;263(15):7190-5.