规格: | 98% |
分子量: | 387.39 |
包装 | 价格(元) |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
Background:
Functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkylC5 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Pomalidomide - linker 3 PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Remillard et al (2017) Degradation of the BAF complex factor BRD9 by heterobifunctional ligands. Angew.Chem.Int.Ed.Engl. 56 5738 PMID:28418626