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Pomalidomide 4'-alkylC5-acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pomalidomide 4'-alkylC5-acid图片
规格:98%
分子量:387.39
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议

产品介绍
Pomalidomide 4'-alkylC5-acid 是一种合成的 E3 连接酶配体-接头偶联物,包含基于 Pomalidomide 的 cereblon 配体和 PROTAC 技术中使用的 PEG 接头。
货号:ajcx27768
CAS:2225940-49-6
分子式:C19H21N3O6
分子量:387.39
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkylC5 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Pomalidomide - linker 3 PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.


Remillard et al (2017) Degradation of the BAF complex factor BRD9 by heterobifunctional ligands. Angew.Chem.Int.Ed.Engl. 56 5738 PMID:28418626