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S4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
S4图片
规格:98%
分子量:335.38
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
High affinity and selective CA IX and CA XII inhibitor
货号:ajcx27128
CAS:1330061-67-0
分子式:C15H17N3O4S
分子量:335.38
溶解度:DMSO: 30 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

High affinity and selective CA IX and CA XII inhibitor (Ki values are 2, 7, 547 and 5600 nM for CA XII, IX, II and I, respectively). Inhibits migration and proliferation of breast cancer cells in vitro. Inhibits lung metastasis in mice bearing breast tumor xenografts, without affecting primary tumor.


Gieling et al (2012) Antimetastatic effect of sulfamate carbonic anhydrase IX inhibitors in breast carcinoma xenografts. J.Med.Chem. 55 5591 PMID:22621623