STOCK2S 26016 是一种 WNK 信号抑制剂。
货号:ajcx27122
CAS:332922-63-1
分子式:C20H19N3O2
分子量：333.38
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Lysine deficient protein kinase (WNK) signaling inhibitor (IC50 = 16 μM). Inhibits binding of WNK1 and WNK4 to SPAK and phosphorylation of downstream transporters, NKCC1 and NCC, in mouse vascular smooth muscle and distal convoluted tubule cell cultures exposed to hypotonic shock, respectively.

Mori et al (2013) Chemical library screening for WNK signalling inhibitors using fluorescence correlation spectroscopy. Biochem.J. 455 339 PMID:23981180