包装: | 1mg |
规格: | 98% |
市场价: | 3185元 |
分子量: | 224.2 |
Background:
Massarigenin C is a fungal metabolite that has been found inM. flavoroseaand has enzyme inhibitory activities.1,2Massarigenin C inhibits neuraminidasein vitro(IC50= 4.15 µM).2It is also an inhibitor of yeast α-glucosidase (IC50= 1.25 mM).1It reduces the postprandial peak in blood glucose levels in an oral sucrose tolerance test in normo- and hyperglycemic mice when administered at doses of 3.2, 10, and 31.6 mg/kg.
1.Verastegui-OmaÑa, B., Rebollar-Ramos, D., PÉrez-VÁsquez, A., et al.α-Glucosidase inhibitors from Malbranchea flavoroseJ. Nat. Prod.80(1)190-195(2017) 2.Zhang, G.F., Han, W.B., Cui, J.T., et al.Neuraminidase inhibitory polyketides from the marine-derived fungus Phoma herbaruPlanta Med.78(1)76-78(2012)