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Curcumin-β-D-glucuronide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Curcumin-β-D-glucuronide图片
规格:98%
分子量:544.5
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
Curcumin-β-D-glucuronide 是口服姜黄素后的主要代谢产物,存在于肝组织和门静脉血中。 Curcumin-β-D-glucuronide 可用于结肠癌的研究。
货号:ajcx35816
CAS:227466-72-0
分子式:C27H28O12
分子量:544.5
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Curcumin-β-D-glucuronide is a major metabolite after oral intake of Curcumin in hepatic tissue and portal blood. Curcumin-β-D-glucuronide can be used for the research of colon cancer[1][2].

Curcumin-β-D-glucuronide (90 mg/kg; i.p. thrice a week for 3 weeks) exhibit potent anti-tumor effects on KRASm/TP53w HCT116 xenograft model[1].

[1]. Ozawa-Umeta H, et, al. Curcumin β-D-glucuronide exhibits anti-tumor effects on oxaliplatin-resistant colon cancer with less toxicity in vivo. Cancer Sci. 2020 May;111(5):1785-1793.
[2]. Ozawa H, et, al. Curcumin β-D-Glucuronide Plays an Important Role to Keep High Levels of Free-Form Curcumin in the Blood. Biol Pharm Bull. 2017;40(9):1515-1524.