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Neuropeptide Y(human)(TFA)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
规格:98%
分子量:4385.7
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
NeuropeptideY(human)TFA和阿尔兹海默症相关,能够保护老鼠皮质神经元对抗淀粉样蛋白毒性。
货号:ajcx31890
CAS:N/A
分子式:C191H286F3N55O59S
分子量:4385.7
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Neuropeptide Y (human) TFA is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.

It is showed that Neuropeptide Y (human) is able to protect cortical neurons from Aβ25-35 toxicity. 2 μM NPY abolishes the toxic effects of Aβ25-35 at 24 and 48 h. The same effect on neuronal survival is observed in neurons exposed to 1 μM and 0.5 μM Neuropeptide Y (human) pretreatments. Pretreatment with Neuropeptide Y (29-64), amide, human (TFA) Increases NGF Synthesis, reduces NGF mRNA, and restores NGF release in cortical neurons exposed to Aβ35-25[1].


[1]. Croce N, et al. Neuropeptide Y protects rat cortical neurons against β-amyloid toxicity and re-establishes synthesis and release of nerve growth factor. ACS Chem Neurosci. 2012 Apr 18;3(4):312-8.