(S)-Seco-DuocarmycinSA是一种DNA烷化剂(DNAalkylator),可作为抗体药物偶联物的毒素部分(ADCcytotoxin)起作用。
货号:ajcx29846
CAS:152785-82-5
分子式:C25H24ClN3O7
分子量:513.93
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
(S)-Seco-Duocarmycin SA is a DNA alkylator, cytotoxic to cancer cells, and acts as a ADC cytotoxin for antibody-drug conjugates[1].
[1]. Tichenor MS, et al. Systematic exploration of the structural features of yatakemycin impacting DNA alkylation and biological activity. J Am Chem Soc. 2007 Sep 5;129(35):10858-69.