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3-hydroxy-4-Methoxyphenethylamine(hydrochloride)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
3-hydroxy-4-Methoxyphenethylamine(hydrochloride)图片
规格:98%
分子量:203.7
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议
250mg电议

产品介绍
A metabolite of dopamine
货号:ajcx28282
CAS:645-33-0
分子式:C9H13NO2 • HCl
分子量:203.7
溶解度:DMF: 5 mg/ml,DMSO: 5 mg/ml,Ethanol: Slightly soluble,PBS (pH 7.2): 10 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

3-hydroxy-4-Methoxyphenethylamine is a metabolite of the catecholamine dopamine .1It is formed from dopamine by catechol-O-methyltransferase (COMT). 3-hydroxy-4-Methoxyphenethylamine (200 µM) decreases the viability of SH-SY5Y cells.2It induces tachycardia and increases blood pressure in normotensive or DOCA-salt hypertensive rats when administered at a dose of 1 mg/kg.33-hydroxy-4-Methoxyphenethylamine (100 mg/kg) induces tremors and rigidity in mice.4

1.Shoup, R.E., Davis, G.C., and Kissinger, P.T.Determination of catechol-O-methyltransferase activity in various tissues by liquid chromatographyAnal. Chem.52(3)483-487(1980) 2.Haque, M.E., Asanuma, M., Higashi, Y., et al.Apoptosis-inducing neurotoxicity of dopamine and its metabolites via reactive quinone generation in neuroblastoma cellsBiochim. Biophys. Acta1619(1)39-52(2003) 3.Gregson, R.P., Lohr, R.R., Marwood, J.F., et al.3-Hydroxy-4-methoxyphenethylamine, the cardioactive constituent of a soft coralExperientia37(5)493-494(1981) 4.Spoerlein, M.T., and VanderWende, C.Nature of the tremors induced by p-methoxydopamineLife Sci.6(19)2029-2035(1967)