Pyridaben 是一种 METI 杀螨剂，可抑制复合物 I 处的线粒体电子传递（METI；Ki = 0.36 nmol/mg 大鼠脑线粒体中的蛋白质）。
货号:ajcx23378
CAS:96489-71-3
分子式:C19H25ClN2OS
分子量：364.9
溶解度:Chloroform: Slightly Soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Pyridaben is a METI acaricide that inhibits mitochondrial electron transport at complex I (METI; K_i= 0.36 nmol/mg protein in rat brain mitochondria).¹It is active against a variety of mites, inducing 100% mortality ofC. malaccensis,D. farina, andT. putrescentiawhen administeredviafilter paper contact at doses of 25, 100, and 200 mg/m³, respectively.²Pyridaben is toxic to rats when administered orally (LD₅₀s = 570 and 1,100 for female and male rats, respectively) andviainhalation (LD₅₀s = 0.62 and 0.66 mg/L for female and male rats, respectively).³Formulations containing pyridaben have been used in the control of mites in agriculture.

1.Navarro, A., BÁndez, M.J., GÓmez, C., et al.Effects of rotenone and pyridaben on complex I electron transfer and on mitochondrial nitric oxide synthase functional activityJ. Bioenerg. Biomembr.42(5)405-412(2010) 2.Takahashi, M., Shono, T., and Umehara, T.Efficacy of pyridaben against three kinds of mites, Cheyletus malaccensis, Dermatophagoides farinae and Tyrophagus putrescentiaeJpn. J. Sanit. Zool.41(3)257-260(1990) 3.Igarashi, H., and Sakamoto, S.Summary of toxicity studies with pyridabenJ. Pest. Scien.19(4)S243-S251(1994)