A neuropeptide with diverse biological activities
货号:ajcx22730
CAS:N/A
分子式:C23H16D5NO2
分子量：348.5
溶解度:DMF: 30 mg/ml,DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml,DMSO: 30 mg/ml,Ethanol: 0.5 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

JWH 073 N-(4-hydroxybutyl) metabolite-d₅contains five deuterium atoms at the 2', 4' ,5', 6', and 7' positions. It is intended for use as an internal standard for the quantification of JWH 073 N-(4-hydroxybutyl) metabolite by GC-or LC-MS. JWH 073 is a mildly selective agonist of the central cannabinoid (CB₁) receptor derived from the aminoalkylindole WIN 55,212-2. The K_ivalues for binding CB₁and the peripheral cannabinoid (CB₂) receptor are 8.9 and 38 nM, respectively for a CB₁:CB₂ratio of 0.23.¹JWH 073 is one of several synthetic CBs which have been included in smoking mixtures. JWH 073 N-(4-hydroxybutyl) metabolite is expected to be a major urinary metabolite of JWH 073, characterized by monohydroxylation of the N-alkyl chain, based on the metabolism of the closely-related JWH 015 and JWH 018.^2,3In urine samples, this metabolite of JWH 018 is almost completely glucuronidated.³

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