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C22 Glucosylceramide-d4(d18:1/22:0-d4)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
C22 Glucosylceramide-d4(d18:1/22:0-d4)图片
规格:98%
分子量:788.2
包装与价格:
包装价格(元)
500ug电议
1mg电议

产品介绍
A neuropeptide with diverse biological activities
货号:ajcx21926
CAS:N/A
分子式:C46H85D4NO8
分子量:788.2
溶解度:
纯度:98%
存储:Store at -20°C
库存:现货

Background:

C22 Glucosylceramide-d4is intended for use as an internal standard for the quantification of C22 glucosylceramide by GC- or LC-MS. C22 Glucosylceramide is an endogenous glucosylceramide.1,2,3Glucosylceramides are major constituents of skin lipid membranes where they play a role in maintaining the water permeability barrier. They are precursors in the synthesis of lactosylceramide , as well as oligoglycolipids and gangliosides. Phospholipase A2(PLA2) type XIIA knockdown increases C22 glucosylceramide expression in rat brain.3It is also increased in the brain, but not the liver or spinal cord, of mice fed a methionine-restricted diet.2In human athletes, plasma levels of C22 glucosylceramide increase during exercise and return to basal levels during recovery.1[Matreya, LLC.]


1.Bergman, B.C., Brozinick, J.T., Strauss, A., et al.Serum sphingolipids: Relationships to insulin sensitivity and changes with exercise in humansAm. J. Physiol. Endocrinol. Metab.309(4)E398-E408(2015) 2.JovÉ, M., Ayala, V., RamÍrez-NÚÑez, O., et al.Specific lipidome signatures in central nervous system from methionine-restricted miceJ. Proteome Res.12(6)2679-2689(2013) 3.Ee, S.-M., Lo, Y.-L., Shui, G., et al.Distribution of secretory phospholipase A2 XIIA in the brain and its role in lipid metabolism and cognitionMol. Neurobiol.50(1)60-75(2014)