An S1P1 receptor agonist
货号:ajcx20412
CAS:2281761-58-6
分子式:C22H37O6P
分子量：428.5
溶解度:DMSO: soluble,Ethanol: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Phospho-ginkgolic acid is an agonist of sphingosine-1-phosphate receptor 1 (S1P1).1 Phospho-ginkgolic acid (10 μM) induces S1P1 receptor internalization and increases ERK phosphorylation in a concentration-dependent manner in CHO cells expressing S1P1.

|1. Swamy, M.M.M., Murai, Y., Ohno, Y., et al. Structure-inspired design of a sphingolipid mimic sphingosine-1-phosphate receptor agonist from a naturally occurring sphingomyelin synthase inhibitor. Chem. Commun. 54(90), 12758-12761 (2018).