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Taraxerone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Taraxerone图片
规格:98%
分子量:424.7
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Taraxerone 是从景天中分离出来的。Taraxerone 增强乙醇脱氢酶 (ADH) 和乙醛脱氢酶 (ALDH) 活性,EC50 值分别为 512.42 μM 和 500.16 μM。
货号:ajcx36006
CAS:514-07-8
分子式:C30H48O
分子量:424.7
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Taraxerone is isolated from Sedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities with EC50 values of 512.42 and 500.16 μM, respectively[1].

Taraxerone significantly lowers the plasma alcohol and acetaldehyde concentrations in mice. Compare to the control group, the ADH and ALDH expressions in the liver tissues are abruptly increased in the taraxerone-treated groups after ethanol exposure[1].Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration[1].

[1]. Sung CK, et al. Taraxerone enhances alcohol oxidation via increases of alcohol dehyderogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities and gene expressions.Food Chem Toxicol. 2012 Jul;50(7):2508-14.