RMC-5552 是一种高效、选择性的 mTORC1 抑制剂。RMC-5552 抑制 mTORC1 底物 pS6K 和 p4EBP1 磷酸化的 IC50 值分别为 0.14 nM 和 0.48 nM。RMC-5552 具有抗肿瘤活性。
货号:ajcx34142
CAS:2382768-62-7
分子式:C93H136N10O24
分子量:1778.13
溶解度:DMSO : 166.67 mg/mL (93.73 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
RMC-5552 is a potent and selective inhibitor of mTORC1. RMC-5552 inhibits phosphorylation of mTORC1 pS6K and p4EBP1 with IC50s of 0.14 nM and 0.48 nM, respectively. RMC-5552 has anti-cancer activity.