2,6-Dichlorodiphenylamine是双氯芬酸钠的结构类似物,具有抗白色念珠菌活性。DiclofenacSodium是一种有效的,非选择性抗炎剂,为 COX的抑制剂,在CHO细胞中,对人COX-1和COX-2的 IC50值分别为4和1.3nM。
货号:ajcx29932
CAS:15307-93-4
分子式:C12H9Cl2N
分子量:238.11
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
2,6-Dichlorodiphenylamine is an analogue of Diclofenac Sodium and has anti-Candida albicans activity. Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells.
[1]. Makoto Urai,et al. Potent Drugs That Attenuate anti-Candida Albicans Activity of Fluconazole and Their Possible Mechanisms of Action. J Infect Chemother. 2014 Oct;20(10):612-5.