Potent PRDM9 inhibitor
货号:ajcx27826
CAS:N/A
分子式:C25H32N6O3
分子量：464.56
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Potent PRDM9 histone methyltransferase inhibitor (IC50 = 85 nM for in vitro methylation of H3K4). Displays >100-fold selectivity over other histone methyltransferases. Inhibits H3K4 methylation in cells (IC50 = 0.8 μM).

Allali-Hassani et al (2019) Discovery of a chemical probe for PRDM9. Nat.Commun. 10 5759 PMID:31848333