TL 13-110 是 TL13-112 的阴性对照,是一种有效的 ALK 抑制剂,IC50 为 0.34 nM。 TL 13-110 不会降解细胞中的 ALK。
货号:ajcx27800
CAS:2229037-09-4
分子式:C49H62ClN9O9S
分子量:988.59
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Negative control for TL 13-112 . Displays no degradation of ALK in cell lines. Highly potent ALK inhibitor (IC50 = 0.34 nM).
Powell et al (2018) Chemically induced degradation of anaplastic lymphoma kinase. J.Med.Chem. 61 4249 PMID:29660984