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VH 032 amide-PEG3-amine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
VH 032 amide-PEG3-amine图片
包装:25mg
规格:98%
市场价:2604元
分子量:692.69

产品介绍
VHL ligand with PEG linker and terminal amine for onward chemistry
货号:ajcx27602
CAS:2376990-24-6
分子式:C30H45N5O7S.2HCl
分子量:692.69
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 1 PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.


Zengerle et al (2015) Selective small molecule induced degradation of the BET bromodomain protein BRD4. ACS Chem. Biol. 10 1770 PMID:26035625 |Salami et al (2017) Waste disposal-An attractive strategy for cancer therapy. Science 355 1163 PMID:28302825