DMNPE-4 AM-caged-calcium 是 EGTA 的光不稳定类似物，是一种非常有效的 Ca2+ 选择性笼，在 pH 7.2 和 pH 7.4 下，Ca2+ 的 Kd 分别为 48 nM 和 19 nM。
货号:ajcx27306
CAS:N/A
分子式:C34H47N3O22
分子量：849.74
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Caged calcium (Kd values are 48 and 19 nM at pH 7.2 and 7.4, respectively; Kd after uncaging = 2 mM). Selective over Mg2+ (Kd =10 mM). Rapid and efficient calcium release upon photolysis at 350 nm. Can also be used for two-photon uncaging. Extinction coefficient of 5120 M-1 cm-1, quantum yield 0.09. Cell permeable.

Wang et al (2015) Spontaneous activity of cochlear hair cells triggered by fluid secretion mechanism in adjacent support cells Cell 163 1348 PMID:26627734 |Gordon et al (2008) Brain metabolism dictates the polarity of astrocyte control over arterioles. Nature 456 745 PMID:18971930 |Ellis-Davies et al (2006) Tuning caged calcium: photolabile analogues of EGTA with improved optical and chelation properties. Cell Calcium 39 75 PMID:16303177