| 规格: | 98% |
| 分子量: | 520.5 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
Background:
FPL 55712 (sodium salt) is a leukotriene (LT) receptor antagonist.1It inhibits the binding of LTD4to guinea pig lung homogenates (IC50= 4 µM) and reduces LTD4-induced contraction of isolated guinea pig tracheal smooth muscle (pA2= 1 µM). FPL 55712 (sodium salt) inhibits bronchoconstriction induced by LTD4, LTC4, or LTE4in guinea pigs (ID50s = 2, 6, and 1 mg/kg, respectively).
1.Cohen, N., Weber, G., Banner, B.L., et al.3,4-Dihydro-2H-1-benzopyran-2-carboxylic acids and related compounds as leukotriene antagonistsJ. Med. Chem.32(8)1842-1860(1989)
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