A fluorogenic substrate for cathepsin L
货号:ajcx25268
CAS:N/A
分子式:C33H36N6O6·XCF3COOH
分子量：612.7
溶解度:DMF: 1 mg/ml,DMSO: 1 mg/ml,Ethanol: 1 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Z-FR-AMC is a fluorogenic substrate for cathepsin L.¹Upon enzymatic cleavage by cathepsin L, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify cathepsin L activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.

1.Carmona, C., Dowd, A.J., Smith, A.M., et al.Cathepsin L proteinase secreted by Fasciola hepatica in vitro prevents antibody-mediated eosinophil attachment to newly excysted juvenilesMol. Biochem. Parasitol.62(1)9-17(1993)