您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Hesperetin-13C-d3
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Hesperetin-13C-d3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Hesperetin-13C-d3图片
规格:98%
分子量:306.3
包装与价格:
包装价格(元)
500ug电议
1mg电议

产品介绍
A neuropeptide with diverse biological activities
货号:ajcx20060
CAS:N/A
分子式:C15[13C]H11D3O6
分子量:306.3
溶解度:Acetonitrile:Methanol (1:1): soluble,DMF: soluble,DMSO: soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Hesperetin-13C-d3 is intended for use as an internal standard for the quantification of hesperetin by GC- or LC-MS. Hesperetin is a citrus flavonoid that has been reported to lower plasma cholesterol.1 Hesperetin reduces the transcription of ACAT2 mRNA in HepG2 cells and reduces ApoB protein synthesis in a dose-dependent manner. The EC50 for these responses is approximately 50 μM. Hesperetin also inhibits histamine release from IgE-challenged RBL-2H3 cells, with a potency comparable to the antihistamine azelastine .2


|1. Wilcox, L.J., Borradaile, N.M., de Dreu, L.E., et al. Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP. J. Lipid Res. 42(5), 725-734 (2001).|2. Lee, N.K., Choi, S.H., Park, S.H., et al. Antiallergic activity of hesperidin is activated by intestinal microflora. Pharmacology 71(4), 174-180 (2004).