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Neurotensin(trifluoroacetate salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Neurotensin(trifluoroacetate salt)图片
包装:1mg
规格:98%
市场价:1122元
分子量:1672.9

产品介绍
Neurotensin is a neuropeptide that is distributed throughout the CNS and in enteroendocrine cells of the small intestine that has diverse biological activities.
货号:ajcx18750
CAS:N/A
分子式:C78H121N21O20•XCF3COOH
分子量:1672.9
溶解度:Water: 1 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Neurotensin is a neuropeptide that is distributed throughout the CNS and in enteroendocrine cells of the small intestine that has diverse biological activities. In vivo, neurotensin (10-50 μg per hour, i.c.v.) induces hypothermia in rats. Neurotensin signaling is increased and induces analgesia in wild-type mice, and neurotensin knockout mice are defective in basal nociceptive and stress-induced analgesic responses in a cold water swim stress test. It acts as an indirect dopamine antagonist that inhibits dopamine-induced effects at pre- and postsynaptic dopamine receptors. Neurotensin inhibits small bowel motility and secretion of gastric acid, stimulates pancreatic and biliary secretion, increases fatty acid absorption, and stimulates growth of the stomach, colon, pancreas, and small bowel in rats. It also increases growth of breast, pancreatic, and hepatocellular carcinoma cells via induction of IL-8 secretion and activation of epithelial mesenchymal transition (EMT) in vitro and in vivo.