AMP-PCP disodium 是一种 ATP 类似物,可以以 Kd 值 为 3.8 μM 来结合到 Hsp90 的 N 末端结构域。AMP-PCP disodium 结合有利于 Hsp90 活性同型二聚体的形成。
货号:ajcx16698
CAS:7414-56-4
分子式:C11H16N5Na2O12P3
分子量:549.17
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
AMP-PCP disodium is an ATP analogue and can bind to Hsp90 N-terminal domain with a Kd value of 3.8 μM. AMP-PCP disodium binding favors the formation of the active homodimer of Hsp90[1].
[1]. Zhang H, et al. A dynamic view of ATP-coupled functioning cycle of Hsp90 N-terminal domain. Sci Rep. 2015 Apr 13;5:9542.