LY-329146 is a selective estrogen receptor modulator (SERM) and is designed to prevent doxorubicin resistance in tumor cells expressing multidrug resistance-associated protein (MRP) by inhibiting the binding of MRP substrates to the estrogen receptor. References: Tawari NR, Bag S, Degani MS. Pharmacophore mapping of a series of pyrrolopyrimidines, indolopyrimidines and their congeners as multidrug-resistance-associated protein (MRP1) modulators. J Mol Model. 2008 Oct;14(10):911-21. doi: 10.1007/s00894-008-0330-z. Epub 2008 Jul 11. PubMed PMID: 18618153.

纯度：≥98%

CAS：191043-78-4