C/EBPα inducer 1 (compound 78) 是 C/EBPα 和骨髓细胞分化的诱导剂。
货号:ajcx33472
CAS:2374285-52-4
分子式:C20H12FN3O4
分子量：377.33
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

C/EBPα inducer 1 (compound 78) is a potent inducer of C/EBPα and myeloid differentiation[1].

C/EBPα inducer 1 (compound 78, 3 μM) causes myeloid differentiation differentiation[1].C/EBPα inducer 1 (compound 78) increases the expression of the neutrophil differentiation surface marker CD11b[1].C/EBPα inducer 1 (compound 78) induces the expression of the neutrophil differentiation surface marker CD11b and upregulation of CEBPA and its downstream targets[1].C/EBPα inducer 1 (compound 78) can upregulate G-CSF receptors, and render leukemic cells more sensitive to G-CSF stimulation[1].

[1]. Radhakrishnan Sridhar, et al. Styryl Quinazolinones as Potential Inducers of Myeloid Differentiation via Upregulation of C/EBPα. Molecules. 2018 Aug 3;23(8):1938.