PD-1/PD-L1 interaction inhibitor
货号:ajcx27646
CAS:1620813-53-7
分子式:C70H98N20O21
分子量：1555.67
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

PD-1/PD-L1 interaction inhibitor. Binds to PD-L1 (Kd = 0.51 μM). Inhibits interaction at 1 mg/mL in flow cytometry. Inhibits tumor growth and prolongs survival time of mice in vivo.

Chang et al (2015) Blocking of the PD-1/PD-L1 interaction by a D-peptide antagonist for cancer immunotherapy. Angew Chem.Int.Ed.Engl. 54 11760 PMID:26259671