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RS 09(trifluoroacetate salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
RS 09(trifluoroacetate salt)图片
规格:98%
分子量:691.8
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议
10mg电议

产品介绍
A TLR4 agonist
货号:ajcx25078
CAS:N/A
分子式:C31H49N9O9·XCF3COOH
分子量:691.8
溶解度:DMF: 1 mg/ml,DMSO: 10 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 1 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

RS 09 is a peptide agonist of toll-like receptor 4 (TLR4).1It activates NF-κB in a concentration-dependent manner in a secreted alkaline phosphatase (SEAP) assay using TLR4-expressing HEK293 cells and induces NF-κB nuclear translocation in the same cells. It also induces cytokine secretion from RAW 264.7 cells. RS 09 (25 µg/animal) acts as an adjuvant in mice vaccinated with a KLH-conjugated X-15 antigen, with no antibodies produced in mice receiving RS 09 without the antigen.


1.Shanmugam, A., Rajoria, S., George, A.L., et al.Synthetic toll like receptor-4 (TLR-4) agonist peptides as a novel class of adjuvantsPLoS One7(2)e30839(2012)