&2#8242;-O-Methylcytidine 是一种 2'-取代的核苷，可作为 HCV 复制的抑制剂。
货号:ajcx24752
CAS:2140-72-9
分子式:C10H15N3O5
分子量：257.2
溶解度:DMSO: 0.2 mg/ml,PBS (pH 7.2): 10 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC₅₀= 3.8 µM).¹It inhibits HCV replication in a replicon assay (IC₅₀= 21.2 µM).

1.Migliaccio, G., Tomassini, J.E., Carroll, S.S., et al.Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitroJ. Bio. Chem.278(49)49164-49170(2003)