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L-Glutamic Acid(ammonium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
L-Glutamic Acid(ammonium salt)图片
规格:98%
分子量:164.2
包装与价格:
包装价格(元)
5g电议
10g电议
25g电议

产品介绍
An excitatory neurotransmitter
货号:ajcx22822
CAS:7558-63-6
分子式:C5H9NO4.NH3
分子量:164.2
溶解度:PBS (pH 7.2): 10 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

L-Glutamic acid is a non-essential amino acid and the primary excitatory neurotransmitter in the CNS.1It acts on ionotropic and metabotropic receptors to induce excitatory synaptic transmission and has roles in synaptic plasticity. Excessive release of L-glutamic acid induces excitotoxicity that is associated with various human diseases, including amyotrophic lateral sclerosis (ALS), stroke, Parkinson's disease, Alzheimer's disease, and Huntington's disease.2Excessive L-glutamic acid release, in its protonated glutamate form, also occurs during seizure activity and contributes to epileptogenesis and seizure-induced brain damage.3


1.Garattini, S.Glutamic acid, twenty years laterJ. Nutr.130(4S Suppl)901S-909S(2000) 2.Greenamyre, J.T.The role of glutamate in neurotransmission and in neurologic diseaseArch. Neurol.43(10)1058-1063(1986) 3.Barker-Haliski, M., and White, H.S.Glutamatergic mechanisms associated with seizures and epilepsyCold Spring Harb. Perspect. Med.5(8)a022863(2015)