A neuropeptide with diverse biological activities
货号:ajcx22716
CAS:N/A
分子式:C24H16D5NO3
分子量：376.5
溶解度:DMF: 30 mg/ml,DMSO: 20 mg/ml,Ethanol: 30 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

JWH 018 N-pentanoic acid metabolite-d₅contains five deuterium atoms at the 2, 4, 5, 6, and 7 positions. It is intended for use as an internal standard for the quantification of JWH 018 N-pentanoic acid metabolite by GC-or LC-mass spectrometry (MS). JWH 018 is a mildly selective agonist of the peripheral cannabinoid (CB₂) receptor, derived from the aminoalkylindole WIN 55,212-2. The K_ivalues for binding central cannabinoid (CB₁) and CB₂receptors are 9.0 and 2.94 nM, respectively, for a CB₁:CB₂ratio of 3.06.¹JWH 018 is one of several synthetic CBs which have been included in smoking mixtures. JWH 018 N-pentanoic acid metabolite is a minor urinary metabolite of JWH 018, characterized by carboxylation of the N-alkyl chain.²In urine samples, this metabolite is almost completely glucuronidated.²

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