MC-DM1 是由 linker MC 和 毒性分子 DM1 连接而成的，可用来制备抗体偶联药物。DM1 (Mertansine)，是含硫醇的美登木素生物碱，是一种有效的微管破坏剂。
货号:ajcx17350
CAS:1375089-56-7
分子式:C42H55ClN4O12
分子量：843.36
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

MC-DM1 is a drug-linker conjugate composed of a potent microtubule-disrupting agent DM1 and a linker MC to make antibody drug conjugate (ADC)[1].

[1]. Shao S, et al. Site-specific and hydrophilic ADCs through disulfide-bridged linker and branched PEG. Bioorg Med Chem Lett. 2018 May 1;28(8):1363-1370.