AT-007 是一种口服活性的,用于治疗半乳糖血症的中枢神经系统 (CNS) 渗透性醛糖还原酶抑制剂, 其 IC50 值为 100 pM。
货号:ajcx15010
CAS:2170729-29-8
分子式:C17H10F3N3O3S2
分子量:425.4
溶解度:DMSO: 35.71 mg/mL (83.94 mM)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase inhibitor for treatment of Galactosemia with an IC50 value of 100 pM[1][2].
[1]. Maeve Conneighton, et al. Applied Therapeutics Announces Initiation of Phase 1/2 Study of AT-007 in Galactosemia.
[2]. UNITED STATES SECURITIES AND EXCHANGE COMMISSION. APPLIED THERAPEUTICS, INC.