Phe-Lys(Trt)-PAB 是一种组织蛋白酶可切割的 ADC 连接桥 (ADC linker),用于抗体偶联药物 (ADCs)。
货号:ajcx14350
CAS:1116085-99-4
分子式:C41H44N4O3
分子量:640.81
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Phe-Lys(Trt)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].
[1]. Abu Ajaj K, et al. Development of protein-binding bifunctional linkers for a new generation of dual-actingprodrugs. Bioconjug Chem. 2009 Feb;20(2):390-6.