MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D 是一种可降解 (cleavable) 的 ADC linker,可用于合成抗体偶联药物 (ADC)。
货号:ajcx37756
CAS:2222445-87-4
分子式:C44H51ClN6O10
分子量:859.36
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.