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(-)-Myrtenal
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(-)-Myrtenal图片
规格:98%
分子量:150.22
包装与价格:
包装价格(元)
500mg电议
1g电议

产品介绍
(-)-Myrtenal ((1R)-(-)-Myrtenal) 是一种口服有效的萜烯,具有抗肿瘤活性。(-)-Myrtenal通过在糖尿病大鼠的骨骼肌和肝脏中通过 Akt 增强 GLUT2 来改善高血糖症。
货号:ajcx35684
CAS:18486-69-6
分子式:C10H14O
分子量:150.22
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

(-)-Myrtenal ((1R)-(-)-Myrtenal) is an orally active terpene with antitumour activity. (-)-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats[1][2].

(-)-Myrtenal ((1R)-(-)-Myrtenal; 0.1-5 mM; for 24 h) exerts strong cytotoxic effect (IC50 = 5.3 mM) on human colon tumour (HT29) and human normal colon epithelial cells (CCD 841 CoTr)[1].

(-)-Myrtenal ((1R)-(-)-Myrtenal; orally; 80 mg/kg/day for 28 days) reveals decreased the levels of plasma glucose, improved the plasma insulin levels, up-regulation of IRS2, Akt and GLUT2 in liver and IRS2, Akt and GLUT4 protein expression in skeletal muscle in diabetic rats induced by single intraperitoneal injection of Streptozotocin (STZ) (40 mg/kg bw)[2].

[1]. Mariusz Trytek, et al. Biological activity of oxygenated pinene derivatives on human colon normal and carcinoma cells. Flavour and Fragrance Journal, Volume33, Issue6, November 2018.
[2]. Ayyasamy Rathinam, et al. Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats. Chem Biol Interact. 2016 Aug 25;256:161-6.